Bitter orange has also been associated with some serious adverse effects, including chest pain, increased blood pressure and heart rate, and anxiety. The National Institutes of Health indicates that safety and adverse side effects of raspberry ketones are not yet known since research on humans is still too limited. There is some research indicating that substances in green tea, such as theanine, may raise your metabolism and curb your appetite. Glucomannan can potentially affect blood sugar, so it's not recommended if you have diabetes.
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